Seminar: Advancing the fields of mechanobiology research and additive manufacturing through dynamic systems and control

Dr. David Hoelzle, The Ohio State University

All dates for this event occur in the past.

E001 Scott Lab
E001 Scott Lab
201 W. 19th Ave.
Columbus, OH 43210
United States

Mechanobiology – the study of the interdependence between cell and tissue mechanics, microenvironment mechanics, and expressed genetics and epigenetics – and additive manufacturing (AM, also termed 3D printing) – a layer-by-layer manufacturing modality – are two disparate fields.  However, they are linked in that both have their predominant physics at the microscale, the process outputs are often in the form of image data, and both have historically leveraged static empirical maps and end-point analysis in their study.  This presentation postulates that the fields of dynamic systems and control have the ability to advance our understanding of mechanobiology and improve AM quality.  The presentation will give a few case studies from the Hoelzle Research Lab at Ohio State.  Recent projects have studied active microsystems designed to mechanically perturb and observe cells and developing epithelial tissues and advanced microscale AM systems that autonomously regulate the process output – fabricated material topography – and compensate for process disturbances.  The presentation will conclude with commentary on future advances that dynamic systems and control may catalyze in both mechanobiology research and AM.

About the Speaker

Prof. David Hoelzle is an Assistant Professor in the Department of Mechanical and Aerospace Engineering at the Ohio State University.  He received his MS and PhD from the University of Illinois at Urbana-Champaign in 2007 and 2011, respectively, in Mechanical Science and Engineering and his BS from the Ohio State University in 2005 in Mechanical Engineering.  Between his PhD and current position, he completed a post-doc in the Department of Integrative Biology and Physiology at the University of California, Los Angeles and held the position of Assistant Professor in the Department of Aerospace and Mechanical Engineering at the University of Notre Dame. His research interests lie in applied control theory and dynamics for applications in additive manufacturing robotics and microsystems for mechanobiology research.  Prof. Hoelzle is a recipient of the 2016 CAREER Award and the 2016 Society of Manufacturing Engineers Outstanding Young Manufacturing Engineer Award.